High Content Screening Analysis

For assay development and screening of non imaging assays refer to assay development and high throughput screening. With an unprecedented flatness whole plate and intra well these microplates are ideal for high resolution cellular imaging applications. The hypercyt high throughput ht flow cytometry sampling platform uses a peristaltic pump in combination with an autosampler and a novel approach to data collection to circumvent time delay bottlenecks of conventional flow cytometry.

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Corning glass bottom and cyclic olefin copolymer coc film bottom high content screening microplates deliver high optical quality for cell based assays.

High content screening analysis.

Assessing a vast number of compounds is time consuming therefore acquiring a large number of high resolution cellular images with fast scanning speed is critically important for drug screening. High content analysis hca high content analysis is a principle methodology for so called phenotypic screening in drug discovery and development process. High content screening hcs also known as high content analysis hca or cellomics is a method that is used in biological research and drug discovery to identify substances such as small molecules peptides or rnai that alter the phenotype of a cell in a desired manner. High content analysis hca or high content screening hcs combines high throughput automated imaging and analysis to extract quantitative multi parametric data at the single cell level.

The hcs team has expertise in all areas of high content image based screens including sample preparation image acquisition image analysis image data management and algorithm development. Hence high content screening is a type of phenotypic screen conducted in cells involving the analysis of whole cells or. This approach also dramatically reduces the amount of sample aspirated for each analysis typically requiring 2 μl per sample while making. Originally developed as a complementary technology to traditional biochemical high throughput screening hts in drug discovery today high content screening.

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